BCL2 Antibody

• Background:

  This gene encodes an integral outer mitochondrial membrane protein that blocks the apoptotic death of some cells such as lymphocytes. Constitutive expression of BCL2, such as in the case of translocation of BCL2 to Ig heavy chain locus, is thought to be the cause of follicular lymphoma. Alternative splicing results in multiple transcript variants.

• NCBI Gene ID:

  596

• Swiss Prot:

  P10415

• Host:

  Rabbit

• Reactivity:

  Human, Mouse, Rat

• Immunogen:

  A synthetic peptide corresponding to a sequence within amino acids 1-100 of human BCL2 (NP_000624.2) .

• Clonality:

  Polyclonal

• Conjugation:

  Unconjugated

• Type:

  Primary Antibodies

• Field of Research:

  Apoptosis, Autophagy, Cancer, Cell Cycle, Immunology, Neuroscience, Signal Transduction, Stem Cell

• Purification:

  Affinity purification

• Positive Control:

  HL-60

• Concentration:

  Batch dependent

• Buffer:

  PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

• Modification:

  None

• Shipping Conditions:

  Blue Ice

• Storage Conditions:

  Store at -20˚ C. Avoid freeze / thaw cycles.

• Calculated Molecular Weight:

  Observed: 28kDa

• Fragment:

  IgG

• Symbol:

  BCL2

• Positive Control 2:

  Jurkat

• Positive Control 3:

  HeLa

• Positive Control 4:

  Mouse lung

• Positive Control 5:

  Mouse testis

• Positive Control 6:

  Rat liver

• NCBI Official Name:

  B-cell CLL/lymphoma 2

• NCBI Organism:

  Homo sapiens

• Other Product Names:

  Bcl-2 Antibody: Bcl-2, PPP1R50, Apoptosis regulator Bcl-2

• Tested Applications:

  WB, IHC, IP

• Physical Properties:

  Liquid