UBE2D2 Antibody

CAT: 0223-13-814Size: 100 µLDry Ice: NoHazardous: No
CAT#:0223-13-814Size:100 µL
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Background
Regulated degradation of misfolded, damaged or short-lived proteins in eukaryotes occurs via the ubiquitin (Ub) -proteasome system (UPS) . An integral part of the UPS system is the ubiquitination of target proteins and covalent linkage of Ub-containing proteins to form polymeric chains, marking them as targets for 26S proteasome-mediated degradation. Ubiquitination of proteins is mediated by a cascade of enzymes which includes E1 (ubiquitin activating), E2 (ubiquitin conjugating), and E3 (ubiquitin ligases) enzymes. This gene encodes a member of the E2 enzyme family. Substrates of this enzyme include the tumor suppressor protein p53 and peroxisomal biogenesis factor 5 (PEX5) . Alternative splicing results in multiple transcript variants of this gene.
NCBI Gene ID
7322
Swiss Prot
P62837
Host
Rabbit
Reactivity
Human, Mouse, Rat
Immunogen
Recombinant fusion protein containing a sequence corresponding to amino acids 1-147 of human UBE2D2 (NP_003330.1) .
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Cell Cycle
Purification
Affinity purification
Positive Control
U-87MG
Concentration
Batch dependent
Buffer
PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at -20˚ C. Avoid freeze / thaw cycles.
Calculated Molecular Weight
Observed: 17kDa
Fragment
IgG
Applications Notes
WB: 1:500 - 1:2000
Symbol
UBE2D2
Positive Control 2
K-562
Positive Control 3
293T
Positive Control 4
Jurkat
Positive Control 5
Mouse testis
Positive Control 6
Mouse brain
NCBI Official Name
Ubiquitin-conjugating enzyme E2D 2
NCBI Organism
Homo sapiens
Other Product Names
UBE2D2, E2 (17) KB2, PUBC1, UBC4, UBC4/5, UBCH5B
Tested Applications
WB
Physical Properties
Liquid

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