MTHFD2 Antibody

• Background :

  This gene encodes a nuclear-encoded mitochondrial bifunctional enzyme with methylenetetrahydrofolate dehydrogenase and methenyltetrahydrofolate cyclohydrolase activities. The enzyme functions as a homodimer and is unique in its absolute requirement for magnesium and inorganic phosphate. Formation of the enzyme-magnesium complex allows binding of NAD. Alternative splicing results in two different transcripts, one protein-coding and the other not protein-coding. This gene has a pseudogene on chromosome 7.

• NCBI Gene ID :

  10797

• Swiss Prot :

  P13995

• Host :

  Rabbit

• Reactivity :

  Human, Mouse, Rat

• Immunogen :

  Recombinant fusion protein containing a sequence corresponding to amino acids 40-250 of human MTHFD2 (NP_006627.2) .

• Clonality :

  Polyclonal

• Conjugation :

  Unconjugated

• Type :

  Primary Antibodies

• Field of Research :

  Other

• Purification :

  Affinity purification

• Positive Control :

  LO2

• Concentration :

  Batch dependent

• Buffer :

  PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

• Modification :

  None

• Shipping Conditions :

  Blue Ice

• Storage Conditions :

  Store at -20˚ C. Avoid freeze / thaw cycles.

• Calculated Molecular Weight :

  Observed: 38kDa

• Fragment :

  IgG

• Symbol :

  MTHFD2

• Positive Control 2 :

  U-87MG

• Positive Control 3 :

  HT-29

• Positive Control 4 :

  293T

• Positive Control 5 :

  DU145

• Positive Control 6 :

  Mouse pancreas

• NCBI Official Name :

  Methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 2, methenyltetrahydrofolate cyclohydrolase

• NCBI Organism :

  Homo sapiens

• Other Product Names :

  MTHFD2, NMDMC

• Tested Applications :

  WB, IHC, IF

• Physical Properties :

  Liquid