PCDH15 Antibody

• Background:

  This gene is a member of the cadherin superfamily. Family members encode integral membrane proteins that mediate calcium-dependent cell-cell adhesion. It plays an essential role in maintenance of normal retinal and cochlear function. Mutations in this gene result in hearing loss and Usher Syndrome Type IF (USH1F) . Extensive alternative splicing resulting in multiple isoforms has been observed in the mouse ortholog. Similar alternatively spliced transcripts are inferred to occur in human, and additional variants are likely to occur.

• NCBI Gene ID:

  65217

• Swiss Prot:

  Q96QU1

• Host:

  Rabbit

• Reactivity:

  Human, Mouse, Rat

• Immunogen:

  Recombinant fusion protein containing a sequence corresponding to amino acids 160-400 of human PCDH15 (NP_001136235.1) .

• Clonality:

  Polyclonal

• Conjugation:

  Unconjugated

• Type:

  Primary Antibodies

• Field of Research:

  Other

• Purification:

  Affinity purification

• Positive Control:

  SH-SY5Y

• Concentration:

  Batch dependent

• Buffer:

  PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

• Modification:

  None

• Shipping Conditions:

  Blue Ice

• Storage Conditions:

  Store at -20˚ C. Avoid freeze / thaw cycles.

• Calculated Molecular Weight:

  Observed: 100kDa

• Fragment:

  IgG

• Symbol:

  PCDH15

• Positive Control 2:

  293T

• Positive Control 3:

  A-549

• Positive Control 4:

  Raji

• Positive Control 5:

  Mouse brain

• Positive Control 6:

  Mouse liver

• NCBI Official Name:

  Protocadherin-related 15

• NCBI Organism:

  Homo sapiens

• Other Product Names:

  PCDH15, RP11-449J3.2, DFNB23, DKFZp667A1711, USH1F, CDHR15

• Tested Applications:

  WB, IHC

• Physical Properties:

  Liquid