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TRAF1 Antibody

CAT: 0223-13-055Size: 100 µLDry Ice: NoHazardous: No
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CAT#:0223-13-055Size:100 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
The protein encoded by this gene is a member of the TNF receptor (TNFR) associated factor (TRAF) protein family. TRAF proteins associate with, and mediate the signal transduction from various receptors of the TNFR superfamily. This protein and TRAF2 form a heterodimeric complex, which is required for TNF-alpha-mediated activation of MAPK8/JNK and NF-kappaB. The protein complex formed by this protein and TRAF2 also interacts with inhibitor-of-apoptosis proteins (IAPs), and thus mediates the anti-apoptotic signals from TNF receptors. The expression of this protein can be induced by Epstein-Barr virus (EBV) . EBV infection membrane protein 1 (LMP1) is found to interact with this and other TRAF proteins; this interaction is thought to link LMP1-mediated B lymphocyte transformation to the signal transduction from TNFR family receptors. Three transcript variants encoding two different isoforms have been found for this gene.
NCBI Gene ID
7185
Swiss Prot
Q13077
Host
Rabbit
Reactivity
Human, Mouse, Rat
Immunogen
Recombinant fusion protein containing a sequence corresponding to amino acids 217-416 of human TRAF1 (NP_005649.1) .
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Apoptosis, Cancer, Cell Cycle, Growth Factors, Signal Transduction
Purification
Affinity purification
Positive Control
SGC-7901
Concentration
Batch dependent
Buffer
PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at -20˚ C. Avoid freeze / thaw cycles.
Calculated Molecular Weight
Observed: 50kDa
Fragment
IgG
Applications Notes
WB: 1:500 - 1:2000
Symbol
TRAF1
Positive Control 2
A-431
Positive Control 3
U-937
Positive Control 4
Jurkat
Positive Control 5
Mouse spleen
Positive Control 6
Rat thymus
NCBI Official Name
TNF receptor-associated factor 1
NCBI Organism
Homo sapiens
Other Product Names
TRAF1, TNF receptor-associated factor 1, EBI6, MGC:10353, Epstein-Bar virus-induced protein 6
Tested Applications
WB
Physical Properties
Liquid

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