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Muromonab-Cd3 (CD3E) - Research Grade Biosimilar

CAT: 0223-10-155Size: 0.1 mgDry Ice: NoHazardous: No
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CAT#:0223-10-155Size:0.1 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
Murine monoclonal antibody specific to CD3 T-cell lymphocyte antigens.More specifically it is a purified murine (mouse) monoclonal antibody, directed against the CD3 (T3) receptor on the surface of human T-cells (T-lymphocytes) cultured using the murine ascites method.Muromonab is 93% monomeric immune globulin G type 2a (IgG2a) .Muromonab binds to the T-cell surface glycoprotein CD3 epsilon chain.It appears to kill CD-3 positive cells by inducing Fc mediated apoptosis, antibody mediated cytotoxicity and complement-dependent cytotoxicity.
Immunogen
Mus musculus / CD3E [Homo sapiens]
Clonality
Recombinant Monoclonal
Conjugation
Unconjugated
Type
Primary Antibodies, Biosimilars
Source
CHO cells
Field of Research
Cancer
Purification
>95%
Concentration
Batch dependent
Buffer
PBS buffer pH7.5
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8 ˚ C for 1-2 weeks. Store at -20 ˚ C for 12 months. Store at -80 ˚ C for long term storage.
Fragment
IgG2a-kappa
NCBI Organism
Homo sapiens
Other Product Names
OKT3

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