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TMEM41B (NT) Antibody

CAT: 0223-9567-01Size: 0.02 mgDry Ice: NoHazardous: No
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CAT#:0223-9567-01Size:0.02 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
TMEM41B Antibody: TMEM41B is required for autophagosome formation and participates in early stages of autophagosome biogenesis at the ER membrane probably via mobilization of neutral lipids from lipid droplets. TMRM41B is a critical host factor required for infection by human coronaviruses SARS-CoV-2, HCoV-OC43, HCoV-NL63, and HCoV-229E, as well as all flaviviruses tested such as Zika virus and Yellow fever virus. It is required post-entry of the virus to facilitate the ER membrane remodeling necessary to form replication organelles.
NCBI Gene ID
440026
Swiss Prot
Q5BJD5
Accession Number
Q5BJD5
Host
Rabbit
Reactivity
Human, Mouse, Rat
Immunogen
9567
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Infectious Disease, COVID-19
Purification
TMEM41B Antibody is affinity chromatography purified via peptide column.
Positive Control
Cat. No. 1203 – A549 Cell Lysate
Concentration
1 mg/mL
Homology
Predicted species reactivity based on immunogen sequence: Horse (100%) ; Chimpanzee (100%) .
Buffer
TMEM41B Antibody is supplied in PBS containing 0.02% sodium azide.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
TMEM41B antibody can be stored at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Fragment
IgG
Symbol
TMEM41B
Positive Control 2
Cat. No. 17-001 - HeLa Cell Slide
NCBI Official Name
Transmembrane protein 41B
NCBI Organism
Homo sapiens
Background Reference 01
Moretti et al. EMBO Rep. 2018; 19 (9) :e45889.
Background Reference 02
Shoemaker et al. PLoS Biol. 2019; 17 (4) :e2007044.
Background Reference 03
Schneider et al. Cell 2021; 184 (1) :120-132.
Background Reference 04
Hoffmann et al. Cell 2021; 184 (1) :133-148.e20.
Other Product Names
TMEM41B Antibody: Transmembrane protein 41B, Protein stasimon, TMEM41B, KIAA0033.
Tested Applications
ELISA, IF, WB
Protein ID
74741383
Physical Properties
Liquid

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