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SLC29A4 Antibody

CAT: 0223-8131-01Size: 0.02 mgDry Ice: NoHazardous: No
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CAT#:0223-8131-01Size:0.02 mg
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Background
SLC29A4 is a member of the equilibrative nucleoside transporter family which plays a key role in nucleoside and nucleobase uptake for salvage pathways of nucleotide synthesis (1,2) . SLC29A4 is a transmembrane protein that catalyzes the reuptake of monoamines into presynaptic neurons, thus determining the intensity and duration of monoamine neural signaling (1,3) . SLC29A4 has been shown to transport several compounds, including serotonin, dopamine, and the neurotoxin 1-methyl-4-phenylpyridinium (3) .
NCBI Gene ID
222962
Swiss Prot
Q7RTT9
Accession Number
NP_001035751
Host
Rabbit
Reactivity
Human
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Cancer, Neuroscience
Purification
SLC29A4 antibody is affinity chromatography purified via peptide column.
Positive Control
Cat. No. 1220 - SK-N-SH Cell Lysate
Concentration
1 mg/mL
Homology
Predicted species reactivity based on immunogen sequence: Mouse: (94%)
Buffer
SLC29A4 antibody is supplied in PBS containing 0.02% sodium azide.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
SLC29A4 antibody can be stored at 4˚ C for three months and -20˚ C, stable for up to one year.
Fragment
IgG
Specificity
SLC29A4 antibody is human specific. SLC29A4 antibody is predicted to not cross-react with other SLC29 proteins.
Symbol
SLC29A4
Positive Control 2
Cat. No. 10-301 - Human Brain Tissue Slide
NCBI Official Name
Solute carrier family 29 (equilibrative nucleoside transporter), member 4
NCBI Organism
Homo sapiens
Background Reference 01
Engel K, Zhou M, and Wang J. Identification and characterization of a novel monomine transporter in the human brain. J. Biol. Chem. 2004; 279:50042-9.
Background Reference 02
Young JD, Yao SY, Baldwin JM, et al. The human concentrative and equilibrative nucleoside transporter families, SLC28 and SLC29. Mol. Aspects. Med. 34:529-47.
Background Reference 03
Duan H and Wang J. Selective transport of monoamine neurotransmitters by human plasma membrane monoamine transporter and organic cation transporter 3. J. Pharmacol. Exp. Ther. 2010; 335:743-53.
Other Product Names
Solute carrier family 29 member 4, Equilibrative nucleoside transporter 4, ENT4, PMAT
Tested Applications
ELISA, WB, IHC-P, IF
Protein ID
100913034
Physical Properties
Liquid

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