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TMIGD1 Antibody

CAT: 0223-7615-01Size: 0.02 mgDry Ice: NoHazardous: No
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CAT#:0223-7615-01Size:0.02 mg
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Background
TMIGD1 (transmembrane and immunoglobulin domain containing 1) is a 262 amino acid single-pass membrane protein that contains two Ig-like C2-type (immunoglobulin-like) domains (1,2) . It is a nonsecreted, glycosylated protein located in the cytoplasm and cell membrane (1) . TMIGD1 might be a possible cell-differentiation marker in the intestine, whose expression is lost during cellular transformation and promote progression of tumorigenesis in the intestinal epithelium (2-4) . TMIGD1 has also been postulated to play a role in cell adhesion (2) .
NCBI Gene ID
388364
Swiss Prot
Q6UXZ0
Accession Number
NP_996663
Host
Rabbit
Reactivity
Human, Mouse, Rat
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Stem Cell
Purification
TMIGD1 antibody is affinity chromatography purified via peptide column.
Positive Control
Cat. No. 1464 - Rat Liver Tissue Lysate
Concentration
1 mg/mL
Homology
Predicted species reactivity based on immunogen sequence: Bovine: (72%)
Buffer
TMIGD1 antibody is supplied in PBS containing 0.02% sodium azide.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
TMIGD1 antibody can be stored at 4˚ C for three months and -20˚ C, stable for up to one year.
Fragment
IgG
Specificity
TMIGD1 antibody is human, mouse and rat reactive. At least two isoforms of TMIGD1 are known to exist; this antibody will detect both isoforms.
Symbol
TMIGD1
NCBI Official Name
Transmembrane and immunoglobulin domain containing 1
NCBI Organism
Homo sapiens
Background Reference 01
Clark HF, Gurney AL, Abaya E, et al. The secreted protein discovery initiative (SPDI), a large-scale effort to identify novel human secreted and transmembrane proteins: a bioinformatics assessment. Genome Res. 2003; 13:2265-70.
Background Reference 02
Fujimoto K, Beauchamp RD, Whitehead RH. Identification and isolation of candidate human colonic clonogenic cells based on cell surface integrin expression. Gastroenterology 2002; 123:1941–8.
Background Reference 03
Yan J, Jiang J, Lim CA, et al. Blimp-1 regulates cell growth through repression of p53 transcription. Proc. Natl. Acad. Sci. USA 2007; 104:1841-6.
Background Reference 04
Cattaneo E, Laczko E, Buffoli F, et al. Preinvasive colorectal lesion transcriptomes correlate with endoscopic morphology (polypoid vs. nonpolypoid) . EMBO Mol Med. 2011; 3:334-47.
Other Product Names
TMIGD1 Antibody: TMIGD, UNQ9372, TMIGD, UNQ9372/PRO34164, Transmembrane and immunoglobulin domain-containing protein 1
Tested Applications
ELISA, WB, IHC-P, IF
Protein ID
45592949
Physical Properties
Liquid

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