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IL-9 Antibody

CAT: 0223-7495-01Size: 0.02 mgDry Ice: NoHazardous: No
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CAT#:0223-7495-01Size:0.02 mg
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Background
Interleukin 9 (IL-9) is a cytokine secreted by TH2 lymphocytes that acts as a regulator of a variety of hematopoietic cells, stimulates cell proliferation and prevents apoptosis (1,2) . It functions through the interleukin 9 receptor (IL9R), which activates different signal transducer and activator (STAT) proteins (3) . The IL-9 gene has been identified as a candidate gene for asthma (4) . Genetic studies on a mouse model of asthma demonstrated that this cytokine is a determining factor in the pathogenesis of bronchial hyperresponsiveness (5) .
NCBI Gene ID
3578
Swiss Prot
P15248
Accession Number
NP_000581
Host
Rabbit
Reactivity
Human
Immunogen
7495
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Validation
Recombinant Protein Test (Figure 2) : Anti-IL-9 antibodies (7495) detected human IL-9 recombinant protein at different concentrations. Recombinant Protein Test7495
Field of Research
Immunology
Purification
IL-9 Antibody is affinity chromatography purified via peptide column.
Positive Control
Cat. No. 1306 - Human Spleen Tissue Lysate
Concentration
1 mg/mL
Buffer
IL-9 Antibody is supplied in PBS containing 0.02% sodium azide.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
IL-9 antibody can be stored at 4˚ C for three months and -20˚ C, stable for up to one year.
Fragment
IgG
Specificity
IL-9 antibody is human specific. IL-9 antibody is predicted to no cross-react with IL-7.
Isoform
Human IL-9 has one isoform (144aa, 16kD) . Mouse IL-9 has one isoform (144aa, 16kD) and Rat IL-9 also has one isoform (144aa, 16kD) . 7495 can detect human isoform, but cannot detect mouse and rat.
Symbol
IL9
Positive Control 2
Cat. No. 10-901 - Human Spleen Tissue Slide
Positive Control 3
Cat. No. 1201 - HeLa Cell Lysate
NCBI Official Name
Interleukin 9
NCBI Organism
Homo sapiens
Background Reference 01
Renauld et al. Cytokine 1990; 2:9-12.
Background Reference 02
Tete et al. J. Biol. Homeost. Agents 2012; 26:319-26.
Background Reference 03
Knoops and Renauld. Growth Factors 2004; 22:207-15.
Background Reference 04
Nicolaides et al. Proc. Natl. Acad. Sci. USA 1997; 94:13175-80.
Other Product Names
IL-9 Antibody : P40, HP40, IL-9, Interleukin-9, Cytokine P40
Tested Applications
ELISA, WB, IHC-P, IF
Protein ID
10834980
Physical Properties
Liquid