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TFPI Antibody

CAT: 0223-7441-01Size: 0.02 mgDry Ice: NoHazardous: No
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CAT#:0223-7441-01Size:0.02 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
TFPI Antibody: Tissue factor pathway inhibitor (TFPI), also known as lipoprotein-associated coagulation inhibitor, is a protease inhibitor that regulates the tissue factor (TF) -dependent pathway of blood coagulation (1) . TFPI is glycosylated and predominantly found in the vascular endothelium and plasma in both free forms and complexed with plasma lipoproteins. The coagulation process initiates with the formation of a factor VIIa-TF complex, which proteolytically activates additional proteases (factors IX and X) and ultimately leads to the formation of a fibrin clot. TFPI inhibits the activated factor X and VIIa-TF proteases in an autoregulatory loop (1) .
NCBI Gene ID
7035
Swiss Prot
P10646
Accession Number
NP_006278
Host
Rabbit
Reactivity
Human, Mouse, Rat
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Signal Transduction
Purification
TFPI Antibody is affinity chromatography purified via peptide column.
Positive Control
Cat. No. 1468 - Rat Small Intestine Tissue Lysate
Concentration
1 mg/mL
Homology
Predicted species reactivity based on immunogen sequence: Rabbit: (92%)
Buffer
TFPI Antibody is supplied in PBS containing 0.02% sodium azide.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
TFPI antibody can be stored at 4˚ C for three months and -20˚ C, stable for up to one year.
Fragment
IgG
Specificity
TFPI antibody is human, mouse and rat reactive. At least two isoforms of TFPI are known to exist; this antibody will detect both isoforms.
Symbol
TFPI
NCBI Official Name
Tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor)
NCBI Organism
Homo sapiens
Background Reference 01
Broze GJ Jr and Girard TJ. Tissue factor pathway inhibitor: structure-function. Front. Biosci. 17:262-80.
Other Product Names
TFPI Antibody: EPI, TFI, LACI, TFPI1, Tissue factor pathway inhibitor, Extrinsic pathway inhibitor, TFPI
Tested Applications
ELISA, WB, IHC-P, IF
Protein ID
5454114
Physical Properties
Liquid

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