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MTERFD3 Antibody

CAT: 0223-7285-01Size: 0.02 mgDry Ice: NoHazardous: No
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CAT#:0223-7285-01Size:0.02 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
MTERFD3 Antibody: Members of the mTERF (mitochondrial transcription termination factor) family, are mitochondrial proteins that are believed to be transcription termination factors. MTERFD3 was initially identified through differential display analysis and is expressed primarily in heart, liver, pancreas and skeletal muscle. MTERFD3 is believed to be involved in cell cycle regulation and cell growth by modulating mitochondrial transcription, and may be a serum-inhibitory factor.
NCBI Gene ID
80298
Swiss Prot
Q49AM1
Accession Number
NP_079474
Host
Rabbit
Reactivity
Human, Mouse
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Cancer, Cell Cycle
Purification
MTERFD3 Antibody is affinity chromatography purified via peptide column.
Positive Control
Cat. No. 1313 - Human Testis Tissue Lysate
Concentration
1 mg/mL
Homology
Predicted species reactivity based on immunogen sequence: Rat: (76%)
Buffer
MTERFD3 Antibody is supplied in PBS containing 0.02% sodium azide.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
MTERFD3 antibody can be stored at 4˚ C for three months and -20˚ C, stable for up to one year.
Fragment
IgG
Specificity
MTERFD3 antibody is predicted to not cross-react with other MTERFD protein family members.
Symbol
MTERFD3
NCBI Official Name
MTERF domain containing 3
NCBI Organism
Homo sapiens
Background Reference 01
Fernandez-Silva P, et al. The human mitochondrial transcription termination factor (mTERF) is a multizipper protein but binds to DNA as a monomer, with evidence pointing to intramolecular leucine zipper interactions. EMBO J. 1997; 16:1066-79.
Background Reference 02
Chen Y, Zhou G, Yu M, et al. Cloning and functional analysis of human mTERFL encoding a novel mitochondrial transcription termination factor-like protein. Biochem. Biophys. Res. Commun. 2005; 337:1112-8.
Background Reference 03
Park CB, Asin-Cayuela J, Camara Y, et al. MTERF3 is a negative regulator of mammalian mtDNA transcription. Cell 2007; 130:273-85.
Other Product Names
MTERFD3 Antibody: mTERF2, mTERFL, mTERF domain-containing protein 3, mitochondrial, Mitochondrial transcription termination factor 2, mTERF2
Tested Applications
ELISA, WB, IHC-P
Protein ID
21314736
Physical Properties
Liquid

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