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MTERFD2 Antibody

CAT: 0223-7283-01Size: 0.02 mgDry Ice: NoHazardous: No
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CAT#:0223-7283-01Size:0.02 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
MTERFD2 Antibody: Members of the mTERF (mitochondrial transcription termination factor) family, are mitochondrial proteins that are believed to be transcription termination factors. MTERFD2 is targeted to the mitochondria and is ubiquitously expressed, with highest expression levels in fore- and midbrain, diencephalon, spinal cord, tongue, lung liver and kidney. MTERFD2 has been suggested to play a role in organ differentiation during embryogenesis. A closely related mTERF family member, MTERFD3, is believed to be involved in cell cycle regulation and cell growth by modulating mitochondrial transcription.
NCBI Gene ID
130916
Swiss Prot
Q7Z6M4
Accession Number
NP_872307
Host
Rabbit
Reactivity
Human, Mouse, Rat
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Stem Cell
Purification
MTERFD2 Antibody is affinity chromatography purified via peptide column.
Positive Control
Cat. No. 1308 - Human Small Intestine Tissue Lysate
Concentration
1 mg/mL
Buffer
MTERFD2 Antibody is supplied in PBS containing 0.02% sodium azide.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
MTERFD2 antibody can be stored at 4˚ C for three months and -20˚ C, stable for up to one year.
Fragment
IgG
Specificity
At least three isoforms of MTERFD2 are known to exist. MTERFD2 antibody is predicted to not cross-react with other MTERFD protein family members.
Symbol
MTERFD2
Positive Control 2
Cat. No. 11-801 - Human Small Intestine Tissue Slide
NCBI Official Name
MTERF domain containing 2
NCBI Organism
Homo sapiens
Background Reference 01
Fernandez-Silva P, et al. The human mitochondrial transcription termination factor (mTERF) is a multizipper protein but binds to DNA as a monomer, with evidence pointing to intramolecular leucine zipper interactions. EMBO J. 1997; 16:1066-79.
Background Reference 02
Xu Q, Zhang F, He H, et al. Expression profile of mouse Mterfd2, a novel component of the mitochondrial transcription termination (MTERF) family. Genes Genet. Syst. 2011; 86:269-75.
Background Reference 03
Park CB, Asin-Cayuela J, Camara Y, et al. MTERF3 is a negative regulator of mammalian mtDNA transcription. Cell 2007; 130:273-85.
Other Product Names
MTERFD2 Antibody: MTERF4, mTERF domain-containing protein 2, Mitochondrial transcription termination factor 4, MTERF4
Tested Applications
ELISA, WB, IHC-P, IF
Protein ID
42740903
Physical Properties
Liquid

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