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TCTEX1D3 Antibody

CAT: 0223-6955-01Size: 0.02 mgDry Ice: NoHazardous: No
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CAT#:0223-6955-01Size:0.02 mg
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Background
TCTEX1D3 Antibody: Dyneins are multi-subunit, high molecular weight ATPases that interact with microtubules to generate force by converting the chemical energy of ATP into the mechanical energy of movement. Cytoplasmic or axonemal Dynein is an approximately 12 subunit complex of two heavy chains, two intermediate chains to anchor Dynein to its cargo, four smaller intermediate chains and several light chains. It performs functions necessary for cell survival such as organelle transport and centrosome assembly. TCTEX1 is a cytoplasmic dynein light chain found in a complex with Na+ CP type X (SCN10A) . TCTEX1D3, also called TCTE3, has been identified as a gene responsible for congenital diaphragmatic hernia (CDH) .
NCBI Gene ID
6991
Swiss Prot
Q8IZS6
Accession Number
NP_777570
Host
Rabbit
Reactivity
Human, Mouse, Rat
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Homeostasis
Purification
TCTEX1D3 Antibody is affinity chromatography purified via peptide column.
Positive Control
Cat. No. 1287 - EL4 Cell Lysate
Concentration
1 mg/mL
Buffer
TCTEX1D3 Antibody is supplied in PBS containing 0.02% sodium azide.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
TCTEX1D3 antibody can be stored at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Calculated Molecular Weight
22 kDa
Fragment
IgG
Specificity
TCTEX1D3 is predicted to not cross-react with other members of the TCTEX-type family
Symbol
TCTE3
Positive Control 2
Cat. No. 11-701 - Human Testis Tissue Slide
NCBI Official Name
T-complex-associated-testis-expressed 3
NCBI Organism
Homo sapiens
Background Reference 01
He Y, Francis F, Myers KA, et al. Role of cytoplasmic dynein in the axonal transport of microtubules and neurofilaments. J. Cell Biol. 2005; 168:697-703.
Background Reference 02
Li J, Lee WL, and Cooper JA. NudEL targets dynein to microtubule ends through LIS1. Nat. Cell Biol. 2005; 7:686-90.
Background Reference 03
Watanabe TK, Fujiwara T, Shimizu F, et al. Cloning, expression, and mapping of TCTEL1, a putative human homologue of murine Tcte1 to 6q. Cytogenet. Cell Genet. 1996; 73:153-6.
Background Reference 04
Chuang JZ, Yeh TY, Bollati F, et al. The dynein light chain Tctex-1 has a dynein-independent role in actin remodeling during neurite outgrowth. Dev. Cell 2005; 9:75-86.
Other Product Names
TCTEX1D3 Antibody: TCTEX1D3, TCTEX1D3, Tctex1 domain-containing protein 3, T-complex testis-specific protein 3, Tcte-3
Tested Applications
ELISA, WB, IF
Protein ID
28372535
Physical Properties
Liquid

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