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TMEM106B Antibody

CAT: 0223-6783-01Size: 0.02 mgDry Ice: NoHazardous: No
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CAT#:0223-6783-01Size:0.02 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
TMEM106B Antibody: Transmembrane protein 106B (TMEM106B) is a single-pass transmembrane protein that is thought to be a novel risk factor for frontotemporal lobar degeneration (FTLD), a group of clinically, pathologically and genetically heterogeneous disorders associated with atrophy in the frontal lobe and temporal lobe of the brain. The actual role of TMEM106B, and that of the closely related protein TMEM106A are still undetermined.
NCBI Gene ID
54664
Swiss Prot
Q9NUM4
Accession Number
NP_060844
Host
Rabbit
Reactivity
Human
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Neuroscience
Purification
TMEM106B Antibody is affinity chromatography purified via peptide column.
Positive Control
Cat. No. 1303 - Human Brain Tissue Lysate
Concentration
1 mg/mL
Homology
Predicted species reactivity based on immunogen sequence: Mouse: (100%), Bovine: (87%), Rat: (86%)
Buffer
TMEM106B Antibody is supplied in PBS containing 0.02% sodium azide.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
TMEM106B antibody can be stored at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Fragment
IgG
Specificity
This TMEM106B antibody is predicted to have no cross-reactivity to TMEM106A.
Symbol
TMEM106B
Positive Control 2
Cat. No. 10-201 - Human Liver Tissue Slide
NCBI Official Name
Transmembrane protein 106B
NCBI Organism
Homo sapiens
Background Reference 01
Van Deerlin VM, Sleiman PM, Martinez-Lage M, et al. Common variants at 7p21 are associated with frontotemporal lobar degeneration with TDP-43 inclusions. Nat. Genet. 2010; 42:234-9.
Background Reference 02
Aswathy PM, Jairani PS, and Mathuranath PS. Genetics of frontotemporal lobar degeneration. Ann. Indian Acad. Neurol. 2010; 13 (Suppl 2) :S55-62.
Other Product Names
TMEM106B Antibody: Transmembrane protein 106B
Tested Applications
ELISA, WB, IHC-P, IF
Protein ID
40254893
Physical Properties
Liquid

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