ZBTB9 Antibody

• Background:

  ZBTB9 Antibody: The ZBTB family of proteins is comprised of diverse zinc finger proteins that also contain a BTB (BR-C, ttk and bab) domain. ZBTB9, also known as ZNF919, is present in multiple tissues, and is highly expressed in the cytoplasm of the placenta. While little is known about ZBTB9, other ZBTB proteins, such as ZBTB4 bind methylated DNA and repress transcription. Another ZBTB proteins, ZBTB7A, has been implicated as a proto-oncogene whose overexpression contributes to malignancy in breast cancer, suggesting that ZBTB9 may act as a transcriptional repressor or be involved in tumorigenesis.

• NCBI Gene ID:

  221504

• Swiss Prot:

  Q96C00

• Accession Number:

  NP_689948

• Host:

  Rabbit

• Reactivity:

  Human, Mouse

• Clonality:

  Polyclonal

• Conjugation:

  Unconjugated

• Type:

  Primary Antibodies

• Field of Research:

  Cancer, Cell Cycle

• Purification:

  ZBTB9 Antibody is affinity chromatography purified via peptide column.

• Positive Control:

  Cat. No. 1401 - Mouse Heart Tissue Lysate

• Concentration:

  1 mg/mL

• Buffer:

  ZBTB9 Antibody is supplied in PBS containing 0.02% sodium azide.

• Modification:

  None

• Shipping Conditions:

  Blue Ice

• Storage Conditions:

  ZBTB9 antibody can be stored at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

• Fragment:

  IgG

• Specificity:

  This antibody is predicted to not cross-react with other ZBTB protein family members.

• Symbol:

  ZBTB9

• NCBI Official Name:

  Zinc finger and BTB domain containing 9

• NCBI Organism:

  Homo sapiens

• Background Reference 01:

  Filion GJP, Zhenilo S, Salozhin S, et al. A family of zinc finger proteins that bind methylated DNA and repress transcription. Mol. Cell. Biol. 2006; 26:169-81.

• Background Reference 02:

  Qu H, Qu D, Chen F, et al. ZBTB7 overexpression contributes to malignancy in breast cancer. Cancer Invest. 2010; 28:672-8.

• Other Product Names:

  ZBTB9 Antibody: ZNF919, Zinc finger and BTB domain-containing protein 9

• Tested Applications:

  ELISA, WB, IHC-P, IF

• Protein ID:

  23308693

• Physical Properties:

  Liquid