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SHISA9 Antibody

CAT: 0223-6057-01Size: 0.02 mgDry Ice: NoHazardous: No
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CAT#:0223-6057-01Size:0.02 mg
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Background
SHISA9 Antibody: Shisa proteins are a recently-identified family of modulators of both FGF and Wnt signaling that block both maturation and transport to the cell surface of their respective receptors. SHISA9, also known as CKAMP44a, is a brain-specific type I transmembrane protein that associates with AMPA receptors in synaptic spines and promotes AMPA receptor desensitization at excitatory synapses. It is thought to modulate short-term plasticity at specific excitatory synapses.
NCBI Gene ID
729993
Swiss Prot
B4DS77
Accession Number
NP_001138676
Host
Rabbit
Reactivity
Human, Mouse, Rat
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Signal Transduction
Purification
SHISA9 Antibody is affinity chromatography purified via peptide column.
Positive Control
Cat. No. 1463 - Rat Brain Tissue Lysate
Concentration
1 mg/mL
Buffer
SHISA9 Antibody is supplied in PBS containing 0.02% sodium azide.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
SHISA9 antibody can be stored at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Fragment
IgG
Symbol
SHISA9
Positive Control 2
Cat. No. 10-301 - Human Brain Tissue Slide
NCBI Official Name
Shisa homolog 9 (Xenopus laevis)
NCBI Organism
Homo sapiens
Background Reference 01
Hedge TA and Mason I. Expression of Shisa2, a modulator of both Wnt and Fgf signaling, in the chick embryo. Int. J. Dev. Biol.2008; 52:81-5.
Background Reference 02
Von Engelhardt J, Mack V, Sprengel R, et al. CKAMP44: a brain-specific protein attenuating short-term synaptic plasticity in the dentate gyrus. Science2010; 327:1518-22.
Background Reference 03
O'Donovan MC, Craddock N, Norton N, et al. Identification of loci associated with schizophrenia by genome-wide association and follow-up. Nat. Genet.2008; 40:1053-5.
Other Product Names
SHISA9 Antibody: CKAMP44, Protein shisa-9
Tested Applications
ELISA, WB, IHC-P, IF
Protein ID
291463300
Physical Properties
Liquid

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