Products for Research Use Only
RegisterLogin

CD81 Antibody

CAT: 0223-5195-01Size: 0.02 mgDry Ice: NoHazardous: No
Product image 1
1 / 1
CAT#:0223-5195-01Size:0.02 mg
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Quick Request Actions
Background
CD81 Antibody: CD81 is a member of the transmembrane 4 superfamily, also known as the tetraspanin family, a group of cell-surface proteins that are characterized by the presence of four hydrophobic domains and mediate signal transduction events that play a role in the regulation of cell development, activation, growth and motility. CD81 is a cell surface glycoprotein that associates with integrins and appears to promote muscle cell fusion and support myotube maintenance. Along with SCARB1, LDL-R, and CLDN1, CD81 has been reported to be an entry factor for the Hepatitis C virus. Finally, recent evidence indicates that the CD81 gene is localized in a tumor-suppressor gene region and is thus a candidate gene for malignancies.
NCBI Gene ID
975
Swiss Prot
P60033
Accession Number
NP_004347
Host
Rabbit
Reactivity
Human, Mouse, Rat
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Infectious Disease
Purification
CD81 Antibody is affinity chromatography purified via peptide column.
Positive Control
Cat. No. 1283 - RAW 264.7 Cell Lysate
Concentration
1 mg/mL
Homology
Predicted species reactivity based on immunogen sequence: Bovine: (95%)
Buffer
CD81 Antibody is supplied in PBS containing 0.02% sodium azide.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
CD81 antibody can be stored at 4˚ C up to one year. Antibodies should not be exposed to prolonged high temperatures.
Fragment
IgG
Symbol
CD81
Positive Control 2
Cat. No. 10-101 - Human Lung Tissue Slide
Positive Control 3
Cat. No. 17-003 - A549 Cell Slide
NCBI Official Name
CD81 molecule
NCBI Organism
Homo sapiens
Background Reference 01
Oren R, Takahashi S, Doss C, et al. TAPA-1, the target of an antiproliferative antibody, defines a new family of transmembrane proteins. Mol. Cell Biol. 1990; 10:4007-15.
Background Reference 02
Charrin S, le Naour F, Silvie O, et al. Lateral organization of membrane proteins: tetraspanins spin their web. Biochem. J. 2009; 420:133-54.
Background Reference 03
Mannion BA, Berditchevski F, Kraeft SK, et al. Transmembrane-4 superfamily proteins CD81 (TAPA-1), CD82, CD63, and CD53 specifically associated with integrin alpha 4 beta 1 (CD49d/CD29) . J. Immunol. 1996; 157:2039-47.
Background Reference 04
Tacvhibana I and Hemler ME. Role of transmembrane 4 superfamily (TM4SF) proteins CD9 and CD81 in muscle cell fusion and myotube maintenance. J. Cell Biol. 1999; 146:893-90.
Other Product Names
CD81 Antibody: S5.7, CVID6, TAPA1, TSPAN28, CD81 antigen, 26 kDa cell surface protein TAPA-1, Tspan-28
Tested Applications
ELISA, WB, IHC-P, IF
Protein ID
4757944
Physical Properties
Liquid

Related Products

CatalogName
5195PCD81 Peptide
42-780CD80 Antibody
57-768CD84 Antibody
8679-01mgCD80 Antibody
18-462CD83 Antibody
56-141CD8B1 Antibody
61-757CD80 Antibody
58-262CD86 Antibody
57-715CD8B Antibody
57-511CD8A Antibody

Alternative Products

CatalogName
abx455618-01CD81 Antigen (CD81) Antibody
A01281-1Anti-CD81 antigen CD81 Antibody
abx341469-01CD81 antigen (CD81) Antibody (Biotin)
abx341467-01CD81 antigen (CD81) Antibody (HRP)
abx341468-01CD81 antigen (CD81) Antibody (FITC)
GWB-A092E6CD81 Antibody
477544CD81 (CD81 Antigen, CD81 Molecule)
477543CD81 (CD81 Antigen

Popular Products