CD81 Antibody [2F7] (PE)

• Background:

  CD81, also known as TAPA-1, is an integral membrane protein expressed on a variety of cell types and has a high degree of sequence homology between human and mouse. CD81 is expressed on thymic stromal cells where it plays an important role in the transition of gammadelta+ T cells to more mature T cells with alphabeta T cell receptors. Immunohistochemical staining has revealed that its expression is localized to the subcapsular region of the thymus and, specifically, on cells that have distinct clustering patterns. It has been speculated that the ligand for CD81 is the pre-T cell receptor which is composed of a TCR beta chain and glycoprotein pTalpha. The monoclonal antibody 2F7 can block thymocyte interaction with CD81 in vitro.

• NCBI Gene ID:

  12520

• Swiss Prot:

  P35762

• Accession Number:

  P35762

• Host:

  Hamster

• Reactivity:

  Mouse

• Immunogen:

  Mouse epithelial cell line PAM212

• Clonality:

  Monoclonal

• Clone:

  [2F7]

• Conjugation:

  PE

• Type:

  Primary Antibodies

• Field of Research:

  Immunology

• Concentration:

  0.1 mg/mL

• Buffer:

  Supplied in PBS/NaN3 and a stabilizing agent

• Modification:

  None

• Shipping Conditions:

  Blue Ice

• Storage Conditions:

  Store vial at 2-8˚ C

• Fragment:

  IgG

• Specificity:

  CD81

• Applications Notes:

  CD81 Antibody [2F7] for use in flow cytometry assays.

• Symbol:

  Cd81

• NCBI Official Name:

  CD81 antigen

• NCBI Organism:

  Mus musculus

• Other Product Names:

  TAPA-1

• Tested Applications:

  Flow

• Physical Properties:

  Liquid