PTER Antibody

• Background:

  PTER Antibody: PTER is a mammalian homolog to bacterial phosphotriesterases, enzymes that hydrolyze phosphotriester-containing organophosphate pesticides. It is expressed primarily in the proximal renal tubules and the gene has been localized in humans to chromosomal band 10p12 by in situ hybridization. PTER, in addition to FTO, MC4R, and NPC1 has recently been shown to be a new risk loci for early-onset and morbid adult obesity in European populations. At least two isoforms of PTER are known to exist.

• NCBI Gene ID:

  9317

• Swiss Prot:

  Q96BW5

• Accession Number:

  CAH73146

• Host:

  Rabbit

• Reactivity:

  Human, Mouse, Rat

• Clonality:

  Polyclonal

• Conjugation:

  Unconjugated

• Type:

  Primary Antibodies

• Field of Research:

  Obesity

• Purification:

  PTER Antibody is affinity chromatography purified via peptide column.

• Positive Control:

  Cat. No. 1305 - Human Kidney Tissue Lysate

• Concentration:

  1 mg/mL

• Homology:

  Predicted species reactivity based on immunogen sequence: Bovine: (88%)

• Buffer:

  PTER Antibody is supplied in PBS containing 0.02% sodium azide.

• Modification:

  None

• Shipping Conditions:

  Blue Ice

• Storage Conditions:

  PTER antibody can be stored at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

• Fragment:

  IgG

• Symbol:

  PTER

• NCBI Official Name:

  Phosphotriesterase related

• NCBI Organism:

  Homo sapiens

• Background Reference 01:

  Davies JA, Buchman VL, Krylova O, et al. Molecular cloning and expression pattern of rpr-1, a resiniferatoxin-binding, phosphotriesterase-related protein, expressed in rat kidney tubules. FEBS Lett.1997; 410:378-82.

• Background Reference 02:

  Alimova-Kost MV, Imreh S, Buchman VL, et al. Assignment of phosphotriesterase-related gene (PTER) to human chromosome band 10p12 by in situ hybridization. Cytogenet.. Cell Genet.1998; 83:16-7.

• Background Reference 03:

  Meyre D, Delplanque J, Chevre JC, et al. Genome-wide associated study for early-onset and morbid adult obesity identifies three new risk loci in European populations. Nat. Genet.2009; 41:157-9.

• Other Product Names:

  PTER Antibody: HPHRP, RPR-1, Phosphotriesterase-related protein, Parathion hydrolase-related protein, hPHRP

• Tested Applications:

  ELISA, WB, IHC-P

• Protein ID:

  55664514

• Physical Properties:

  Liquid