ACE2 Antibody

• Background :

  COVID-19 (2019-nCoV) may use ACE2 as a receptor in humans

• NCBI Gene ID :

  59272

• Swiss Prot :

  Q9BYF1

• Accession Number :

  NP_068576

• Host :

  Rabbit

• Reactivity :

  Human, Mouse, Rat

• Clonality :

  Polyclonal

• Conjugation :

  Unconjugated

• Type :

  Primary Antibodies

• Field of Research :

  Infectious Disease

• Purification :

  ACE2 Antibody is affinity chromatography purified via peptide column.

• Positive Control :

  Cat. No. 1305 - Human Kidney Tissue Lysate

• Concentration :

  1 mg/mL

• Homology :

  Predicted species reactivity based on immunogen sequence: Bovine: (93%)

• Buffer :

  ACE2 Antibody is supplied in PBS containing 0.02% sodium azide.

• Modification :

  None

• Shipping Conditions :

  Blue Ice

• Storage Conditions :

  ACE2 antibody can be stored at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

• Fragment :

  IgG

• Specificity :

  Anti-ACE2 has no cross response to ACE1.

• Isoform :

  Human ACE2 has 2 isoforms, including isoform 1 (805aa, 93kD) and isoform 2 (555aa, 64kD) . Mouse ACE2 also has 2 isoforms, including isoform 1 (805aa, 92kD) and isoform 2 (353aa, 40kD) . Rat ACE2 has one isoform (805aa, 93kD) . 3229 can detect human, mouse and rat.

• Symbol :

  ACE2

• Positive Control 2 :

  Cat. No. 10-401 - Human Kidney Tissue Slide

• NCBI Official Name :

  Angiotensin I converting enzyme (peptidyl-dipeptidase A) 2

• NCBI Organism :

  Homo sapiens

• Background Reference 01 :

  Donoghue et al. Circ. Res. 2000;87:1-9.

• Background Reference 02 :

  Tipnis et al. J Biol. Chem. 2000;275:33238-43.

• Background Reference 03 :

  Li et al. Nature 2003;426:450-4.

• Background Reference 04 :

  Lu et al. The Lancet 2020 (published online) .

• Background Reference 05 :

  Crackower et al. Nature 2002;417:822-8.

• Other Product Names :

  ACE2 Antibody: ACEH, Angiotensin-converting enzyme 2, ACE-related carboxypeptidase, ACEH, SARS-CoV receptor, SARS-CoV-2 receptor

• Tested Applications :

  ELISA, WB, IHC-P, IF

• Protein ID :

  11225609

• Physical Properties :

  Liquid