Human ACE2 Recombinant Protein

• Background:

  Angiotensin-Converting Enzyme 2 (ACE-2) is an integral membrane protein and a zinc metalloprotease of the ACE family, the ACE family includes somatic and germinal ACE. ACE-2 cleaves angiotensins I and II as a carboxypeptidase, ACE-2 converts angiotensin I to angiotensin 1-9, and angiotensin II to angiotensin 1-7. ACE-2 is also able to hydrolyze apelin-13 and dynorphin-13 with high efficiency. ACE-2 can be high expressed in testis, kidney and heart, in colon, small intestine and ovary at moderate levels. Captopril and lisinopril as the classical ACE inhibitor don’t inhibit ACE-2 activity. ACE-2 may play an important role in regulating the heart function.

• Accession Number:

  NP_001358344.1 or Uniprot Q9BYF1

• Tag:

  Without Tag

• Type:

  Recombinant Proteins

• Source:

  Mammalian Cells

• Field of Research:

  Infectious Disease

• Purity:

  >90% as determined by SDS-PAGE

• Buffer:

  Supplied as lyophilized from TBS, pH 8.0. Please reconstitute the protein with ddH2O to the concentration with 1mg/ml.

• Shipping Conditions:

  Room Temp

• Storage Conditions:

  Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8 ˚ C for one week. Store at -20 to -80 ˚ C for twelve months from the date of receipt.

• Calculated Molecular Weight:

  85.2kDa

• Applications Notes:

  Immunogen

• Other Product Names:

  ACE-related carboxypeptidase, Angiotensin-converting enzyme homolog, Metalloprotease MPROT15

• Species:

  Human

• Physical Properties:

  Lyophilized

• CAS Number:

  9000-83-3