Lincomycin (hydrochloride monohydrate)

Lincomycin (hydrochloride monohydrate)

• CAS Number: 7179-49-9
• UNSPSC Description: Lincomycin hydrochloride monohydrate is a narrow-spectrum antibiotic, has similar effects to erythromycin, which has a good effect on gram-positive coccus, mainly used to inhibit the synthesis of bacterial cell protein[1][2].
• Target Antigen: Antibiotic; Bacterial
• Type: Natural Products
• Related Pathways: Anti-infection
• Applications: COVID-19-immunoregulation
• Field of Research: Infection
• Assay Protocol: https://www.medchemexpress.com/Lincomycin-hydrochloride-hydrate.html
• Purity: 99.29
• Solubility: DMSO : ≥ 100 mg/mL|H2O : 50 mg/mL (ultrasonic)
• Smiles: C[C@@H](O)[C@](NC([C@H]1N(C)C[C@H](CCC)C1)=O)([H])[C@@]2([H])O[C@H](SC)[C@H](O)[C@@H](O)[C@H]2O.Cl.O
• Molecular Weight: 461.01
• References & Citations: [1]MACLEOD AJ, et al. LINCOMYCIN: A NEW ANTIBIOTIC ACTIVE AGAINST STAPHYLOCOCCI AND OTHER GRAM-POSITIVE COCCI: CLINICAL AND LABORATORY STUDIES. Can Med Assoc J. 1964 Nov 14;91:1056-60.|[2]Lin AH, et al. The oxazolidinone eperezolid binds to the 50S ribosomal subunit and competes with binding of chloramphenicol and lincomycin. Antimicrob Agents Chemother. 1997 Oct;41(10):2127-31.|[3]P R McMaster, et al. The effect of two chlorinated lincomycin analogues against acute toxoplasmosis in mice. Am J Trop Med Hyg. 1973 Jan;22(1):14-7.
• Shipping Conditions: Room Temperature
• Storage Conditions: 4°C (Powder, sealed storage, away from moisture)
• Clinical Information: Launched