Mmp14 (NM_008608) Mouse Recombinant Protein

• Background:

  This gene encodes a member of the matrix metalloproteinase family of extracellular matrix-degrading enzymes that are involved in tissue remodeling, wound repair, progression of atherosclerosis and tumor invasion. The encoded preproprotein undergoes proteolytic processing to generate a mature, zinc-dependent endopeptidase enzyme. Mice lacking the encoded protein exhibit craniofacial dysmorphism, arthritis, osteopenia, dwarfism, and fibrosis of soft tissues. [provided by RefSeq, Feb 2016]

• Synonyms:

  AI325305; MMP-X1; MT-MMP-1; MT1-MM; MT1-MMP; sa; sabe

• Gene ID:

  17387

• UniProt:

  P53690

• Accession Number mRNA:

  NM_008608

• Chromosomal Location:

  14 27.79 cM

• Expression System:

  HEK293T

• Tag:

  C-MYC/DDK

• Concentration:

  >50 ug/mL as determined by microplate BCA method

• Purity:

  > 80% as determined by SDS-PAGE and Coomassie blue staining

• Form:

  Liquid

• Buffer:

  25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol.

• Molecular Weight:

  66.4 kDa

• Storage Conditions:

  Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.

• Symbol:

  Mmp14

• Species:

  Mouse

• Protein ID:

  NP_032634

• Overview:

  Purified recombinant protein of Mouse matrix metallopeptidase 14 (membrane-inserted) (Mmp14), with C-terminal MYC/DDK tag, expressed in HEK293T cells, 20ug

• Gene ID URL:

  https://www.ncbi.nlm.nih.gov/gene/17387

• Uniprot URL:

  https://www.uniprot.org/uniprot/P53690

• Accession Number mRNA URL:

  https://www.ncbi.nlm.nih.gov/nuccore/NM_008608

• Protein ID Link:

  https://www.ncbi.nlm.nih.gov/nuccore/NP_032634