CERT1 (NM_031361) Human Recombinant Protein

• Background:

  This gene encodes a kinase that specifically phosphorylates the N-terminal region of the non-collagenous domain of the alpha 3 chain of type IV collagen, known as the Goodpasture antigen. Goodpasture disease is the result of an autoimmune response directed at this antigen. One isoform of this protein is also involved in ceramide intracellular transport. Three transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]

• Synonyms:

  CERT; CERTL; COL4A3BP; GPBP; MRD34; STARD11

• Gene ID:

  10087

• UniProt:

  Q9Y5P4, A0A024RAJ5

• Accession Number mRNA:

  NM_031361

• Chromosomal Location:

  5q13.3

• Expression System:

  HEK293T

• Tag:

  C-Myc/DDK

• Concentration:

  >50 ug/mL as determined by microplate BCA method

• Purity:

  > 80% as determined by SDS-PAGE and Coomassie blue staining

• Form:

  Liquid

• Buffer:

  25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol

• Molecular Weight:

  67.8 kDa

• Storage Conditions:

  Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.

• Symbol:

  CERT1

• Species:

  Human

• Protein ID:

  NP_112729

• Overview:

  Recombinant protein of human collagen, type IV, alpha 3 (Goodpasture antigen) binding protein (COL4A3BP), transcript variant 2

• Gene ID URL:

  https://www.ncbi.nlm.nih.gov/gene/10087

• Uniprot URL:

  https://www.uniprot.org/uniprot/Q9Y5P4

• Accession Number mRNA URL:

  https://www.ncbi.nlm.nih.gov/nuccore/NM_031361

• Protein ID Link:

  https://www.ncbi.nlm.nih.gov/nuccore/NP_112729