AP3S2 (NM_005829) Human Recombinant Protein

• Background:

  Part of the AP-3 complex, an adaptor-related complex which is not clathrin-associated. The complex is associated with the Golgi region as well as more peripheral structures. It facilitates the budding of vesicles from the Golgi membrane and may be directly involved in trafficking to lysosomes. In concert with the BLOC-1 complex, AP-3 is required to target cargos into vesicles assembled at cell bodies for delivery into neurites and nerve terminals.[UniProtKB/Swiss-Prot Function]

• Synonyms:

  AP3S3; sigma3b

• Gene ID:

  10239

• UniProt:

  P59780, A0A024RC62

• Accession Number mRNA:

  NM_005829

• Chromosomal Location:

  15q26.1

• Expression System:

  HEK293T

• Tag:

  C-Myc/DDK

• Related Pathways:

  Lysosome

• Field of Research:

  Lysosome

• Concentration:

  >50 ug/mL as determined by microplate BCA method

• Purity:

  > 80% as determined by SDS-PAGE and Coomassie blue staining

• Form:

  Liquid

• Buffer:

  25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol

• Molecular Weight:

  21.8 kDa

• Storage Conditions:

  Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.

• Symbol:

  AP3S2

• Species:

  Human

• Protein ID:

  NP_005820

• Overview:

  Recombinant protein of human adaptor-related protein complex 3, sigma 2 subunit (AP3S2)

• Gene ID URL:

  https://www.ncbi.nlm.nih.gov/gene/10239

• Uniprot URL:

  https://www.uniprot.org/uniprot/P59780

• Accession Number mRNA URL:

  https://www.ncbi.nlm.nih.gov/nuccore/NM_005829

• Protein ID Link:

  https://www.ncbi.nlm.nih.gov/nuccore/NP_005820