ELAVL1 (NM_001419) Human Recombinant Protein

• Background:

  The protein encoded by this gene is a member of the ELAVL family of RNA-binding proteins that contain several RNA recognition motifs, and selectively bind AU-rich elements (AREs) found in the 3' untranslated regions of mRNAs. AREs signal degradation of mRNAs as a means to regulate gene expression, thus by binding AREs, the ELAVL family of proteins play a role in stabilizing ARE-containing mRNAs. This gene has been implicated in a variety of biological processes and has been linked to a number of diseases, including cancer. It is highly expressed in many cancers, and could be potentially useful in cancer diagnosis, prognosis, and therapy. [provided by RefSeq, Sep 2012]

• Synonyms:

  ELAV1; Hua; HUR; MelG

• Gene ID:

  1994

• UniProt:

  Q15717

• Accession Number mRNA:

  NM_001419

• Chromosomal Location:

  19p13.2

• Expression System:

  HEK293T

• Tag:

  C-Myc/DDK

• Concentration:

  >50 ug/mL as determined by microplate BCA method

• Purity:

  > 80% as determined by SDS-PAGE and Coomassie blue staining

• Activity:

  27609814

• Form:

  Liquid

• Buffer:

  25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol

• Molecular Weight:

  35.9 kDa

• Storage Conditions:

  Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.

• Symbol:

  ELAVL1

• Species:

  Human

• Protein ID:

  NP_001410

• Overview:

  Recombinant protein of human ELAV (embryonic lethal, abnormal vision, Drosophila) -like 1 (Hu antigen R) (ELAVL1)

• Gene ID URL:

  https://www.ncbi.nlm.nih.gov/gene/1994

• Uniprot URL:

  https://www.uniprot.org/uniprot/Q15717

• Accession Number mRNA URL:

  https://www.ncbi.nlm.nih.gov/nuccore/NM_001419

• Protein ID Link:

  https://www.ncbi.nlm.nih.gov/nuccore/NP_001410