CMBL (NM_138809) Human Recombinant Protein

• Background:

  CMBL (EC 3.1.1.45) is a cysteine hydrolase of the dienelactone hydrolase family that is highly expressed in liver cytosol. CMBL preferentially cleaves cyclic esters, and it activates medoxomil-ester prodrugs in which the medoxomil moiety is linked to an oxygen atom (Ishizuka et al., 2010 [PubMed 20177059]) .[supplied by OMIM, Apr 2010]

• Synonyms:

  JS-1

• Gene ID:

  134147

• UniProt:

  Q96DG6

• Accession Number mRNA:

  NM_138809

• Chromosomal Location:

  5p15.2

• Expression System:

  HEK293T

• Tag:

  C-Myc/DDK

• Related Pathways:

  Metabolic pathways

• Field of Research:

  Metabolic pathways

• Concentration:

  >50 ug/mL as determined by microplate BCA method

• Purity:

  > 80% as determined by SDS-PAGE and Coomassie blue staining

• Form:

  Liquid

• Buffer:

  25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol

• Molecular Weight:

  27.9 kDa

• Storage Conditions:

  Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.

• Symbol:

  CMBL

• Species:

  Human

• Protein ID:

  NP_620164

• Overview:

  Recombinant protein of human carboxymethylenebutenolidase homolog (Pseudomonas) (CMBL)

• Gene ID URL:

  https://www.ncbi.nlm.nih.gov/gene/134147

• Uniprot URL:

  https://www.uniprot.org/uniprot/Q96DG6

• Accession Number mRNA URL:

  https://www.ncbi.nlm.nih.gov/nuccore/NM_138809

• Protein ID Link:

  https://www.ncbi.nlm.nih.gov/nuccore/NP_620164