GALT (NM_000155) Human Recombinant Protein

• Background:

  Galactose-1-phosphate uridyl transferase (GALT) catalyzes the second step of the Leloir pathway of galactose metabolism, namely the conversion of UDP-glucose + galactose-1-phosphate to glucose-1-phosphate + UDP-galactose. The absence of this enzyme results in classic galactosemia in humans and can be fatal in the newborn period if lactose is not removed from the diet. The pathophysiology of galactosemia has not been clearly defined. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Apr 2012]

• Synonyms:

  Galactose-1-phosphate uridyl transferase; galactose-1-phosphate uridylyltransferase; OTTHUMP00000021298

• Gene ID:

  2592

• UniProt:

  P07902, A0A0S2Z3Y7, B2RAT6

• Accession Number mRNA:

  NM_000155

• Chromosomal Location:

  9p13.3

• Expression System:

  HEK293T

• Tag:

  C-Myc/DDK

• Related Pathways:

  Amino sugar and nucleotide sugar metabolism, Galactose metabolism, Metabolic pathways

• Field of Research:

  Amino sugar and nucleotide sugar metabolism, Galactose metabolism, Metabolic pathways

• Concentration:

  >50 ug/mL as determined by microplate BCA method

• Purity:

  > 80% as determined by SDS-PAGE and Coomassie blue staining

• Form:

  Liquid

• Buffer:

  25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol

• Function:

  Druggable Genome

• Molecular Weight:

  43.2 kDa

• Storage Conditions:

  Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.

• Symbol:

  GALT

• Species:

  Human

• Protein ID:

  NP_000146

• Overview:

  Recombinant protein of human galactose-1-phosphate uridylyltransferase (GALT)

• Gene ID URL:

  https://www.ncbi.nlm.nih.gov/gene/2592

• Uniprot URL:

  https://www.uniprot.org/uniprot/P07902

• Accession Number mRNA URL:

  https://www.ncbi.nlm.nih.gov/nuccore/NM_000155

• Protein ID Link:

  https://www.ncbi.nlm.nih.gov/nuccore/NP_000146