IFNGR1 (NM_000416) Human Recombinant Protein

• Background:

  This gene (IFNGR1) encodes the ligand-binding chain (alpha) of the gamma interferon receptor. Human interferon-gamma receptor is a heterodimer of IFNGR1 and IFNGR2. A genetic variation in IFNGR1 is associated with susceptibility to Helicobacter pylori infection. In addition, defects in IFNGR1 are a cause of mendelian susceptibility to mycobacterial disease, also known as familial disseminated atypical mycobacterial infection. [provided by RefSeq, Jul 2008]

• Synonyms:

  CD119; IFNGR; IMD27A; IMD27B

• Gene ID:

  3459

• UniProt:

  P15260, A0A0S2Z3Y2

• Accession Number mRNA:

  NM_000416

• Chromosomal Location:

  6q23.3

• Expression System:

  HEK293T

• Tag:

  C-Myc/DDK

• Related Pathways:

  Cytokine-cytokine receptor interaction, Jak-STAT signaling pathway, Natural killer cell mediated cytotoxicity

• Field of Research:

  Cytokine-cytokine receptor interaction, Jak-STAT signaling pathway, Natural killer cell mediated cytotoxicity

• Concentration:

  >50 ug/mL as determined by microplate BCA method

• Purity:

  > 80% as determined by SDS-PAGE and Coomassie blue staining

• Form:

  Liquid

• Buffer:

  25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol

• Function:

  Druggable Genome, ES Cell Differentiation/IPS, Transmembrane

• Molecular Weight:

  52.5 kDa

• Storage Conditions:

  Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.

• Symbol:

  IFNGR1

• Species:

  Human

• Protein ID:

  NP_000407

• Overview:

  Recombinant protein of human interferon gamma receptor 1 (IFNGR1)

• Gene ID URL:

  https://www.ncbi.nlm.nih.gov/gene/3459

• Uniprot URL:

  https://www.uniprot.org/uniprot/P15260

• Accession Number mRNA URL:

  https://www.ncbi.nlm.nih.gov/nuccore/NM_000416

• Protein ID Link:

  https://www.ncbi.nlm.nih.gov/nuccore/NP_000407