ASCC2 (NM_032204) Human Recombinant Protein

• Background:

  Plays a role in DNA damage repair as component of the ASCC complex. Recruits ASCC3 and ALKBH3 to sites of DNA damage by binding to polyubiquitinated proteins that have 'Lys-63'-linked polyubiquitin chains (PubMed:29144457) . Part of the ASC-1 complex that enhances NF-kappa-B, SRF and AP1 transactivation (PubMed:12077347) .[UniProtKB/Swiss-Prot Function]

• Synonyms:

  ASC1p100; p100

• Gene ID:

  84164

• UniProt:

  Q9H1I8, A0A024R1F9

• Accession Number mRNA:

  NM_032204

• Chromosomal Location:

  22q12.2

• Expression System:

  HEK293T

• Tag:

  C-Myc/DDK

• Concentration:

  >50 ug/mL as determined by microplate BCA method

• Purity:

  > 80% as determined by SDS-PAGE and Coomassie blue staining

• Form:

  Liquid

• Buffer:

  25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol

• Function:

  Druggable Genome, Transcription Factors

• Molecular Weight:

  86.2 kDa

• Storage Conditions:

  Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.

• Symbol:

  ASCC2

• Species:

  Human

• Protein ID:

  NP_115580

• Overview:

  Recombinant protein of human activating signal cointegrator 1 complex subunit 2 (ASCC2)

• Gene ID URL:

  https://www.ncbi.nlm.nih.gov/gene/84164

• Uniprot URL:

  https://www.uniprot.org/uniprot/Q9H1I8

• Accession Number mRNA URL:

  https://www.ncbi.nlm.nih.gov/nuccore/NM_032204

• Protein ID Link:

  https://www.ncbi.nlm.nih.gov/nuccore/NP_115580