OXCT1 (NM_000436) Human Recombinant Protein

• Background:

  This gene encodes a member of the 3-oxoacid CoA-transferase gene family. The encoded protein is a homodimeric mitochondrial matrix enzyme that plays a central role in extrahepatic ketone body catabolism by catalyzing the reversible transfer of coenzyme A from succinyl-CoA to acetoacetate. Mutations in this gene are associated with succinyl CoA:3-oxoacid CoA transferase deficiency. [provided by RefSeq, Jul 2008]

• Synonyms:

  OXCT; SCOT

• Gene ID:

  5019

• UniProt:

  P55809, A0A024R040

• Accession Number mRNA:

  NM_000436

• Chromosomal Location:

  5p13.1

• Expression System:

  HEK293T

• Tag:

  C-Myc/DDK

• Related Pathways:

  Butanoate metabolism, Synthesis and degradation of ketone bodies, Valine, leucine and isoleucine degradation

• Field of Research:

  Butanoate metabolism, Synthesis and degradation of ketone bodies, Valine, leucine and isoleucine degradation

• Concentration:

  >50 ug/mL as determined by microplate BCA method

• Purity:

  > 80% as determined by SDS-PAGE and Coomassie blue staining

• Form:

  Liquid

• Buffer:

  25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol

• Molecular Weight:

  52 kDa

• Storage Conditions:

  Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.

• Symbol:

  OXCT1

• Species:

  Human

• Protein ID:

  NP_000427

• Overview:

  Recombinant protein of human 3-oxoacid CoA transferase 1 (OXCT1), nuclear gene encoding mitochondrial protein

• Gene ID URL:

  https://www.ncbi.nlm.nih.gov/gene/5019

• Uniprot URL:

  https://www.uniprot.org/uniprot/P55809

• Accession Number mRNA URL:

  https://www.ncbi.nlm.nih.gov/nuccore/NM_000436

• Protein ID Link:

  https://www.ncbi.nlm.nih.gov/nuccore/NP_000427