MITD1 (NM_138798) Human Recombinant Protein

• Background:

  Abscission, the separation of daughter cells at the end of cytokinesis, is effected by endosomal sorting complexes required for transport III (ESCRT-III) . The protein encoded by this gene functions as a homodimer, with the N-termini binding to a subset of ESCRT-III subunits and the C-termini binding to membranes. The encoded protein regulates ESCRT-III activity and is required for proper cytokinesis. Several transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Feb 2016]

• Synonyms:

  Domain containing 1; microtubule interacting and transport; MIT

• Gene ID:

  129531

• UniProt:

  Q8WV92

• Accession Number mRNA:

  NM_138798

• Chromosomal Location:

  2q11.2

• Expression System:

  HEK293T

• Tag:

  C-Myc/DDK

• Concentration:

  >50 ug/mL as determined by microplate BCA method

• Purity:

  > 80% as determined by SDS-PAGE and Coomassie blue staining

• Form:

  Liquid

• Buffer:

  25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol

• Molecular Weight:

  29.1 kDa

• Storage Conditions:

  Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.

• Symbol:

  MITD1

• Species:

  Human

• Protein ID:

  NP_620153

• Overview:

  Recombinant protein of human MIT, microtubule interacting and transport, domain containing 1 (MITD1)

• Gene ID URL:

  https://www.ncbi.nlm.nih.gov/gene/129531

• Uniprot URL:

  https://www.uniprot.org/uniprot/Q8WV92

• Accession Number mRNA URL:

  https://www.ncbi.nlm.nih.gov/nuccore/NM_138798

• Protein ID Link:

  https://www.ncbi.nlm.nih.gov/nuccore/NP_620153