Neuroligin 4 (NLGN4X) (NM_181332) Human Recombinant Protein

• Background:

  This gene encodes a member of the type-B carboxylesterase/lipase protein family. The encoded protein belongs to a family of neuronal cell surface proteins. Members of this family may act as splice site-specific ligands for beta-neurexins and may be involved in the formation and remodeling of central nervous system synapses. The encoded protein interacts with discs large homolog 4 (DLG4) . Mutations in this gene have been associated with autism and Asperger syndrome. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Aug 2013]

• Synonyms:

  ASPGX2; AUTSX2; HLNX; HNL4X; NLGN4

• Gene ID:

  57502

• UniProt:

  Q8N0W4, A0A024RBV0

• Accession Number mRNA:

  NM_181332

• Chromosomal Location:

  Xp22.32-p22.31

• Expression System:

  HEK293T

• Tag:

  C-Myc/DDK

• Related Pathways:

  Cell adhesion molecules (CAMs)

• Field of Research:

  Cell adhesion molecules (CAMs)

• Concentration:

  >50 ug/mL as determined by microplate BCA method

• Purity:

  > 80% as determined by SDS-PAGE and Coomassie blue staining

• Form:

  Liquid

• Buffer:

  25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol

• Function:

  Druggable Genome, Transmembrane

• Molecular Weight:

  91.7 kDa

• Storage Conditions:

  Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.

• Symbol:

  NLGN4X

• Species:

  Human

• Protein ID:

  NP_851849

• Overview:

  Recombinant protein of human neuroligin 4, X-linked (NLGN4X), transcript variant 2

• Gene ID URL:

  https://www.ncbi.nlm.nih.gov/gene/57502

• Uniprot URL:

  https://www.uniprot.org/uniprot/Q8N0W4

• Accession Number mRNA URL:

  https://www.ncbi.nlm.nih.gov/nuccore/NM_181332

• Protein ID Link:

  https://www.ncbi.nlm.nih.gov/nuccore/NP_851849