TKTL2 (NM_032136) Human Recombinant Protein

• Background:

  Plays an essential role in total transketolase activity and cell proliferation in cancer cells; after transfection with anti-TKTL1 siRNA, total transketolase activity dramatically decreases and proliferation was significantly inhibited in cancer cells. Plays a pivotal role in carcinogenesis.[UniProtKB/Swiss-Prot Function]

• Synonyms:

  DKFZp434L1717; FLJ32975

• Gene ID:

  84076

• UniProt:

  Q9H0I9, A0A140VKC2

• Accession Number mRNA:

  NM_032136

• Chromosomal Location:

  4q32.2

• Expression System:

  HEK293T

• Tag:

  C-Myc/DDK

• Related Pathways:

  Metabolic pathways, Pentose phosphate pathway

• Field of Research:

  Metabolic pathways, Pentose phosphate pathway

• Concentration:

  >50 ug/mL as determined by microplate BCA method

• Purity:

  > 80% as determined by SDS-PAGE and Coomassie blue staining

• Form:

  Liquid

• Buffer:

  25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol

• Molecular Weight:

  67.7 kDa

• Storage Conditions:

  Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.

• Symbol:

  TKTL2

• Species:

  Human

• Protein ID:

  NP_115512

• Overview:

  Recombinant protein of human transketolase-like 2 (TKTL2)

• Gene ID URL:

  https://www.ncbi.nlm.nih.gov/gene/84076

• Uniprot URL:

  https://www.uniprot.org/uniprot/Q9H0I9

• Accession Number mRNA URL:

  https://www.ncbi.nlm.nih.gov/nuccore/NM_032136

• Protein ID Link:

  https://www.ncbi.nlm.nih.gov/nuccore/NP_115512