FBLIM1 (NM_017556) Human Recombinant Protein

• Background:

  This gene encodes a protein with an N-terminal filamin-binding domain, a central proline-rich domain, and, multiple C-terminal LIM domains. This protein localizes at cell junctions and may link cell adhesion structures to the actin cytoskeleton. This protein may be involved in the assembly and stabilization of actin-filaments and likely plays a role in modulating cell adhesion, cell morphology and cell motility. This protein also localizes to the nucleus and may affect cardiomyocyte differentiation after binding with the CSX/NKX2-5 transcription factor. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Jul 2008]

• Synonyms:

  CAL; FBLP-1; FBLP1

• Gene ID:

  54751

• UniProt:

  Q8WUP2

• Accession Number mRNA:

  NM_017556

• Chromosomal Location:

  1p36.21

• Expression System:

  HEK293T

• Tag:

  C-Myc/DDK

• Concentration:

  >50 ug/mL as determined by microplate BCA method

• Purity:

  > 80% as determined by SDS-PAGE and Coomassie blue staining

• Form:

  Liquid

• Buffer:

  25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol

• Molecular Weight:

  40.5 kDa

• Storage Conditions:

  Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.

• Symbol:

  FBLIM1

• Species:

  Human

• Protein ID:

  NP_060026

• Overview:

  Recombinant protein of human filamin binding LIM protein 1 (FBLIM1), transcript variant 1

• Gene ID URL:

  https://www.ncbi.nlm.nih.gov/gene/54751

• Uniprot URL:

  https://www.uniprot.org/uniprot/Q8WUP2

• Accession Number mRNA URL:

  https://www.ncbi.nlm.nih.gov/nuccore/NM_017556

• Protein ID Link:

  https://www.ncbi.nlm.nih.gov/nuccore/NP_060026