Fblim1 (NM_133754) Mouse Recombinant Protein

• Background:

  Serves as an anchoring site for cell-ECM adhesion proteins and filamin-containing actin filaments. Is implicated in cell shape modulation (spreading) and motility. May participate in the regulation of filamin-mediated cross-linking and stabilization of actin filaments. May also regulate the assembly of filamin-containing signaling complexes that control actin assembly. Promotes dissociation of FLNA from ITGB3 and ITGB7. Promotes activation of integrins and regulates integrin-mediated cell-cell adhesion (By similarity) .[UniProtKB/Swiss-Prot Function]

• Synonyms:

  2410043F08Rik; Cal; Fblp1; Gt10; migfilin; migfilin (s)

• Gene ID:

  74202

• UniProt:

  Q71FD7

• Accession Number mRNA:

  NM_133754

• Chromosomal Location:

  4 D3

• Expression System:

  HEK293T

• Tag:

  C-MYC/DDK

• Concentration:

  >50 ug/mL as determined by microplate BCA method

• Purity:

  > 80% as determined by SDS-PAGE and Coomassie blue staining

• Form:

  Liquid

• Buffer:

  25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol.

• Molecular Weight:

  41 kDa

• Storage Conditions:

  Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.

• Symbol:

  Fblim1

• Species:

  Mouse

• Protein ID:

  NP_598515

• Overview:

  Purified recombinant protein of Mouse filamin binding LIM protein 1 (Fblim1), with C-terminal MYC/DDK tag, expressed in HEK293T cells, 20ug

• Gene ID URL:

  https://www.ncbi.nlm.nih.gov/gene/74202

• Uniprot URL:

  https://www.uniprot.org/uniprot/Q71FD7

• Accession Number mRNA URL:

  https://www.ncbi.nlm.nih.gov/nuccore/NM_133754

• Protein ID Link:

  https://www.ncbi.nlm.nih.gov/nuccore/NP_598515