TSPYL5 (NM_033512) Human Recombinant Protein

• Background:

  Involved in modulation of cell growth and cellular response to gamma radiation probably via regulation of the Akt signaling pathway. Involved in regulation of p53/TP53. Suppresses p53/TP53 protein levels and promotes its ubiquitination; the function is dependent on USP7 and independent on MDM2. Proposed to displace p53/TP53 from interaction with USP7.[UniProtKB/Swiss-Prot Function]

• Synonyms:

  KIAA1750

• Gene ID:

  85453

• UniProt:

  Q86VY4

• Accession Number mRNA:

  NM_033512

• Chromosomal Location:

  8q22.1

• Expression System:

  HEK293T

• Tag:

  C-Myc/DDK

• Concentration:

  >50 ug/mL as determined by microplate BCA method

• Purity:

  > 80% as determined by SDS-PAGE and Coomassie blue staining

• Form:

  Liquid

• Buffer:

  25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol

• Molecular Weight:

  45 kDa

• Storage Conditions:

  Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.

• Symbol:

  TSPYL5

• Species:

  Human

• Protein ID:

  NP_277047

• Overview:

  Purified recombinant protein of Homo sapiens TSPY-like 5 (TSPYL5)

• Gene ID URL:

  https://www.ncbi.nlm.nih.gov/gene/85453

• Uniprot URL:

  https://www.uniprot.org/uniprot/Q86VY4

• Accession Number mRNA URL:

  https://www.ncbi.nlm.nih.gov/nuccore/NM_033512

• Protein ID Link:

  https://www.ncbi.nlm.nih.gov/nuccore/NP_277047