EHHADH (NM_001966) Human Recombinant Protein

• Background:

  The protein encoded by this gene is a bifunctional enzyme and is one of the four enzymes of the peroxisomal beta-oxidation pathway. The N-terminal region of the encoded protein contains enoyl-CoA hydratase activity while the C-terminal region contains 3-hydroxyacyl-CoA dehydrogenase activity. Defects in this gene are a cause of peroxisomal disorders such as Zellweger syndrome. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Oct 2009]

• Synonyms:

  ECHD; FRTS3; L-PBE; LBFP; LBP; MFE1; PBFE

• Gene ID:

  1962

• UniProt:

  Q08426

• Accession Number mRNA:

  NM_001966

• Chromosomal Location:

  3q27.2

• Expression System:

  HEK293T

• Tag:

  C-Myc/DDK

• Related Pathways:

  Beta-Alanine metabolism, Butanoate metabolism, Fatty acid metabolism, Limonene and pinene degradation, Lysine degradation, Metabolic pathways, PPAR signaling pathway, Propanoate metabolism, Tryptophan metabolism, Valine, leucine and isoleucine degradation

• Field of Research:

  Beta-Alanine metabolism, Butanoate metabolism, Fatty acid metabolism, Limonene and pinene degradation, Lysine degradation, Metabolic pathways, PPAR signaling pathway, Propanoate metabolism, Tryptophan metabolism, Valine, leucine and isoleucine degradation

• Concentration:

  >50 ug/mL as determined by microplate BCA method

• Purity:

  > 80% as determined by SDS-PAGE and Coomassie blue staining

• Form:

  Liquid

• Buffer:

  25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol

• Molecular Weight:

  79.3 kDa

• Storage Conditions:

  Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.

• Symbol:

  EHHADH

• Species:

  Human

• Protein ID:

  NP_001957

• Overview:

  Recombinant protein of human enoyl-Coenzyme A, hydratase/3-hydroxyacyl Coenzyme A dehydrogenase (EHHADH)

• Gene ID URL:

  https://www.ncbi.nlm.nih.gov/gene/1962

• Uniprot URL:

  https://www.uniprot.org/uniprot/Q08426

• Accession Number mRNA URL:

  https://www.ncbi.nlm.nih.gov/nuccore/NM_001966

• Protein ID Link:

  https://www.ncbi.nlm.nih.gov/nuccore/NP_001957