XRCC2 (NM_005431) Human Recombinant Protein

• Background:

  This gene encodes a member of the RecA/Rad51-related protein family that participates in homologous recombination to maintain chromosome stability and repair DNA damage. This gene is involved in the repair of DNA double-strand breaks by homologous recombination and it functionally complements Chinese hamster irs1, a repair-deficient mutant that exhibits hypersensitivity to a number of different DNA-damaging agents. [provided by RefSeq, Jul 2008]

• Synonyms:

  FANCU; POF17; SPGF50

• Gene ID:

  7516

• UniProt:

  O43543, A0A384MEK2

• Accession Number mRNA:

  NM_005431

• Chromosomal Location:

  7q36.1

• Expression System:

  HEK293T

• Tag:

  C-Myc/DDK

• Related Pathways:

  Homologous recombination

• Field of Research:

  Homologous recombination

• Concentration:

  >50 ug/mL as determined by microplate BCA method

• Purity:

  > 80% as determined by SDS-PAGE and Coomassie blue staining

• Form:

  Liquid

• Buffer:

  25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol

• Function:

  Druggable Genome

• Molecular Weight:

  31.8 kDa

• Storage Conditions:

  Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.

• Symbol:

  XRCC2

• Species:

  Human

• Protein ID:

  NP_005422

• Overview:

  Recombinant protein of human X-ray repair complementing defective repair in Chinese hamster cells 2 (XRCC2)

• Gene ID URL:

  https://www.ncbi.nlm.nih.gov/gene/7516

• Uniprot URL:

  https://www.uniprot.org/uniprot/O43543

• Accession Number mRNA URL:

  https://www.ncbi.nlm.nih.gov/nuccore/NM_005431

• Protein ID Link:

  https://www.ncbi.nlm.nih.gov/nuccore/NP_005422