IL1RAP (NM_134470) Human Recombinant Protein

• Background:

  This gene encodes a component of the interleukin 1 receptor complex, which initiates signalling events that result in the activation of interleukin 1-responsive genes. Alternative splicing of this gene results in membrane-bound and soluble isoforms differing in their C-terminus. The ratio of soluble to membrane-bound forms increases during acute-phase induction or stress. [provided by RefSeq, Jul 2018]

• Synonyms:

  C3orf13; IL-1RAcP; IL1R3

• Gene ID:

  3556

• UniProt:

  Q9NPH3

• Accession Number mRNA:

  NM_134470

• Chromosomal Location:

  3q28

• Expression System:

  HEK293T

• Tag:

  C-Myc/DDK

• Related Pathways:

  Apoptosis, Cytokine-cytokine receptor interaction

• Field of Research:

  Apoptosis, Cytokine-cytokine receptor interaction

• Concentration:

  >50 ug/mL as determined by microplate BCA method

• Purity:

  > 80% as determined by SDS-PAGE and Coomassie blue staining

• Form:

  Liquid

• Buffer:

  25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol

• Function:

  Druggable Genome, Secreted Protein, Transmembrane

• Molecular Weight:

  40.8 kDa

• Storage Conditions:

  Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.

• Symbol:

  IL1RAP

• Species:

  Human

• Protein ID:

  NP_608273

• Overview:

  Recombinant protein of human interleukin 1 receptor accessory protein (IL1RAP), transcript variant 2

• Gene ID URL:

  https://www.ncbi.nlm.nih.gov/gene/3556

• Uniprot URL:

  https://www.uniprot.org/uniprot/Q9NPH3

• Accession Number mRNA URL:

  https://www.ncbi.nlm.nih.gov/nuccore/NM_134470

• Protein ID Link:

  https://www.ncbi.nlm.nih.gov/nuccore/NP_608273