GRK5 (NM_005308) Human Recombinant Protein

• Background:

  This gene encodes a member of the guanine nucleotide-binding protein (G protein) -coupled receptor kinase subfamily of the Ser/Thr protein kinase family. The protein phosphorylates the activated forms of G protein-coupled receptors thus initiating their deactivation. It has also been shown to play a role in regulating the motility of polymorphonuclear leukocytes (PMNs) . [provided by RefSeq, Jul 2008]

• Synonyms:

  FP2025; GPRK5

• Gene ID:

  2869

• UniProt:

  P34947

• Accession Number mRNA:

  NM_005308

• Chromosomal Location:

  10q26.11

• Expression System:

  HEK293T

• Tag:

  C-Myc/DDK

• Related Pathways:

  Chemokine signaling pathway, Endocytosis

• Field of Research:

  Chemokine signaling pathway, Endocytosis

• Concentration:

  >50 ug/mL as determined by microplate BCA method

• Purity:

  > 80% as determined by SDS-PAGE and Coomassie blue staining

• Form:

  Liquid

• Buffer:

  25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol

• Function:

  Druggable Genome, Protein Kinase

• Molecular Weight:

  67.6 kDa

• Storage Conditions:

  Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.

• Symbol:

  GRK5

• Species:

  Human

• Protein ID:

  NP_005299

• Overview:

  Recombinant protein of human G protein-coupled receptor kinase 5 (GRK5)

• Gene ID URL:

  https://www.ncbi.nlm.nih.gov/gene/2869

• Uniprot URL:

  https://www.uniprot.org/uniprot/P34947

• Accession Number mRNA URL:

  https://www.ncbi.nlm.nih.gov/nuccore/NM_005308

• Protein ID Link:

  https://www.ncbi.nlm.nih.gov/nuccore/NP_005299