PITRM1 (NM_014889) Human Recombinant Protein

• Background:

  The protein encoded by this gene is an ATP-dependent metalloprotease that degrades post-cleavage mitochondrial transit peptides. The encoded protein binds zinc and can also degrade amyloid beta A4 protein, suggesting a possible role in Alzheimer's disease. [provided by RefSeq, Dec 2016]

• Synonyms:

  MP1; PreP

• Gene ID:

  10531

• UniProt:

  Q5JRX3

• Accession Number mRNA:

  NM_014889

• Chromosomal Location:

  10p15.2

• Expression System:

  HEK293T

• Tag:

  C-Myc/DDK

• Concentration:

  >50 ug/mL as determined by microplate BCA method

• Purity:

  > 80% as determined by SDS-PAGE and Coomassie blue staining

• Form:

  Liquid

• Buffer:

  25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol

• Function:

  Druggable Genome, Protease

• Molecular Weight:

  117.2 kDa

• Storage Conditions:

  Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.

• Symbol:

  PITRM1

• Species:

  Human

• Protein ID:

  NP_055704

• Overview:

  Recombinant protein of human pitrilysin metallopeptidase 1 (PITRM1)

• Gene ID URL:

  https://www.ncbi.nlm.nih.gov/gene/10531

• Uniprot URL:

  https://www.uniprot.org/uniprot/Q5JRX3

• Accession Number mRNA URL:

  https://www.ncbi.nlm.nih.gov/nuccore/NM_014889

• Protein ID Link:

  https://www.ncbi.nlm.nih.gov/nuccore/NP_055704