TNFSF18 (NM_005092) Human Recombinant Protein

• Background:

  The protein encoded by this gene is a cytokine that belongs to the tumor necrosis factor (TNF) ligand family. This cytokine is a ligand for receptor TNFRSF18/AITR/GITR. It has been shown to modulate T lymphocyte survival in peripheral tissues. This cytokine is also found to be expressed in endothelial cells, and is thought to be important for interaction between T lymphocytes and endothelial cells. [provided by RefSeq, Jul 2008]

• Synonyms:

  AITRL; GITRL; hGITRL; TL6; TNLG2A

• Gene ID:

  8995

• UniProt:

  Q9UNG2, A0A0U5JXL4

• Accession Number mRNA:

  NM_005092

• Chromosomal Location:

  1q25.1

• Expression System:

  HEK293T

• Tag:

  C-Myc/DDK

• Related Pathways:

  Cytokine-cytokine receptor interaction

• Field of Research:

  Cytokine-cytokine receptor interaction

• Concentration:

  >50 ug/mL as determined by microplate BCA method

• Purity:

  > 80% as determined by SDS-PAGE and Coomassie blue staining

• Form:

  Liquid

• Buffer:

  25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol

• Function:

  Druggable Genome, Transmembrane

• Molecular Weight:

  22.5 kDa

• Storage Conditions:

  Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.

• Symbol:

  TNFSF18

• Species:

  Human

• Protein ID:

  NP_005083

• Overview:

  Recombinant protein of human tumor necrosis factor (ligand) superfamily, member 18 (TNFSF18)

• Gene ID URL:

  https://www.ncbi.nlm.nih.gov/gene/8995

• Uniprot URL:

  https://www.uniprot.org/uniprot/Q9UNG2

• Accession Number mRNA URL:

  https://www.ncbi.nlm.nih.gov/nuccore/NM_005092

• Protein ID Link:

  https://www.ncbi.nlm.nih.gov/nuccore/NP_005083