ORC4L (ORC4) (NM_181741) Human Recombinant Protein

• Background:

  The origin recognition complex (ORC) is a highly conserved six subunit protein complex essential for the initiation of the DNA replication in eukaryotic cells. Studies in yeast demonstrated that ORC binds specifically to origins of replication and serves as a platform for the assembly of additional initiation factors such as Cdc6 and Mcm proteins. This gene encodes a subunit of the ORC complex. Several alternatively spliced transcript variants, some of which encode the same protein, have been reported for this gene. [provided by RefSeq, Oct 2010]

• Synonyms:

  ORC4L; ORC4P

• Gene ID:

  5000

• UniProt:

  O43929

• Accession Number mRNA:

  NM_181741

• Chromosomal Location:

  2q23.1

• Expression System:

  HEK293T

• Tag:

  C-Myc/DDK

• Related Pathways:

  Cell cycle

• Field of Research:

  Cell cycle

• Concentration:

  >50 ug/mL as determined by microplate BCA method

• Purity:

  > 80% as determined by SDS-PAGE and Coomassie blue staining

• Form:

  Liquid

• Buffer:

  25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol

• Molecular Weight:

  50.2 kDa

• Storage Conditions:

  Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.

• Symbol:

  ORC4

• Species:

  Human

• Protein ID:

  NP_859525

• Overview:

  Recombinant protein of human origin recognition complex, subunit 4-like (yeast) (ORC4L), transcript variant 1

• Gene ID URL:

  https://www.ncbi.nlm.nih.gov/gene/5000

• Uniprot URL:

  https://www.uniprot.org/uniprot/O43929

• Accession Number mRNA URL:

  https://www.ncbi.nlm.nih.gov/nuccore/NM_181741

• Protein ID Link:

  https://www.ncbi.nlm.nih.gov/nuccore/NP_859525