Orc4 (NM_011958) Mouse Recombinant Protein

• Background:

  Binds histone H3 and H4 trimethylation marks H3K9me3, H3K27me3 and H4K20me3 (By similarity) . Component of the origin recognition complex (ORC) that binds origins of replication. DNA-binding is ATP-dependent. The specific DNA sequences that define origins of replication have not been identified yet. ORC is required to assemble the pre-replication complex necessary to initiate DNA replication.[UniProtKB/Swiss-Prot Function]

• Synonyms:

  MMmORC4; Orc4l; Orc4P

• Gene ID:

  26428

• UniProt:

  O88708

• Accession Number mRNA:

  NM_011958

• Chromosomal Location:

  2 C1.1

• Expression System:

  HEK293T

• Tag:

  C-MYC/DDK

• Concentration:

  >50 ug/mL as determined by microplate BCA method

• Purity:

  > 80% as determined by SDS-PAGE and Coomassie blue staining

• Form:

  Liquid

• Buffer:

  25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol.

• Molecular Weight:

  50 kDa

• Storage Conditions:

  Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.

• Symbol:

  Orc4

• Species:

  Mouse

• Protein ID:

  NP_036088

• Overview:

  Purified recombinant protein of Mouse origin recognition complex, subunit 4 (Orc4), with C-terminal MYC/DDK tag, expressed in HEK293T cells, 20ug

• Gene ID URL:

  https://www.ncbi.nlm.nih.gov/gene/26428

• Uniprot URL:

  https://www.uniprot.org/uniprot/O88708

• Accession Number mRNA URL:

  https://www.ncbi.nlm.nih.gov/nuccore/NM_011958

• Protein ID Link:

  https://www.ncbi.nlm.nih.gov/nuccore/NP_036088