DNALI1 (NM_003462) Human Recombinant Protein

• Background:

  This gene is the human homolog of the Chlamydomonas inner dynein arm gene, p28. The precise function of this gene is not known, however, it is a potential candidate for immotile cilia syndrome (ICS) . Ultrastructural defects of the inner dynein arms are seen in patients with ICS. Immotile mutant strains of Chlamydomonas, a biflagellated algae, exhibit similar defects. [provided by RefSeq, Jul 2008]

• Synonyms:

  DJ423B22.5; hp28; P28

• Gene ID:

  7802

• UniProt:

  O14645, A0A499FIY3

• Accession Number mRNA:

  NM_003462

• Chromosomal Location:

  1p34.3

• Expression System:

  HEK293T

• Tag:

  C-Myc/DDK

• Related Pathways:

  Huntington's disease

• Field of Research:

  Huntington's disease

• Concentration:

  >50 ug/mL as determined by microplate BCA method

• Purity:

  > 80% as determined by SDS-PAGE and Coomassie blue staining

• Form:

  Liquid

• Buffer:

  25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol

• Molecular Weight:

  31.7 kDa

• Storage Conditions:

  Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.

• Symbol:

  DNALI1

• Species:

  Human

• Protein ID:

  NP_003453

• Overview:

  Recombinant protein of human dynein, axonemal, light intermediate chain 1 (DNALI1)

• Gene ID URL:

  https://www.ncbi.nlm.nih.gov/gene/7802

• Uniprot URL:

  https://www.uniprot.org/uniprot/O14645

• Accession Number mRNA URL:

  https://www.ncbi.nlm.nih.gov/nuccore/NM_003462

• Protein ID Link:

  https://www.ncbi.nlm.nih.gov/nuccore/NP_003453