Menin (MEN1) (NM_130799) Human Recombinant Protein

• Background:

  This gene encodes menin, a tumor suppressor associated with a syndrome known as multiple endocrine neoplasia type 1. Menin is a scaffold protein that functions in histone modification and epigenetic gene regulation. It is thought to regulate several pathways and processes by altering chromatin structure through the modification of histones. [provided by RefSeq, May 2019]

• Synonyms:

  MEAI; SCG2

• Gene ID:

  4221

• UniProt:

  O00255, A0A024R5E3

• Accession Number mRNA:

  NM_130799

• Chromosomal Location:

  11q13.1

• Expression System:

  HEK293T

• Tag:

  C-Myc/DDK

• Concentration:

  >50 ug/mL as determined by microplate BCA method

• Purity:

  > 80% as determined by SDS-PAGE and Coomassie blue staining

• Form:

  Liquid

• Buffer:

  25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol

• Function:

  Druggable Genome, Transcription Factors

• Molecular Weight:

  67.3 kDa

• Storage Conditions:

  Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.

• Symbol:

  MEN1

• Species:

  Human

• Protein ID:

  NP_570711

• Overview:

  Recombinant protein of human multiple endocrine neoplasia I (MEN1), transcript variant 2

• Gene ID URL:

  https://www.ncbi.nlm.nih.gov/gene/4221

• Uniprot URL:

  https://www.uniprot.org/uniprot/O00255

• Accession Number mRNA URL:

  https://www.ncbi.nlm.nih.gov/nuccore/NM_130799

• Protein ID Link:

  https://www.ncbi.nlm.nih.gov/nuccore/NP_570711