P16 ARC (ARPC5) (NM_005717) Human Recombinant Protein

• Background:

  This gene encodes one of seven subunits of the human Arp2/3 protein complex. The Arp2/3 protein complex has been implicated in the control of actin polymerization in cells and has been conserved through evolution. The exact role of the protein encoded by this gene, the p16 subunit, has yet to be determined. Alternatively spliced transcript variants encoding different isoforms have been observed for this gene. [provided by RefSeq, Jul 2012]

• Synonyms:

  ARC16; dJ127C7.3; p16-Arc

• Gene ID:

  10092

• UniProt:

  O15511

• Accession Number mRNA:

  NM_005717

• Chromosomal Location:

  1q25.3

• Expression System:

  HEK293T

• Tag:

  C-Myc/DDK

• Related Pathways:

  Fc gamma R-mediated phagocytosis, Pathogenic Escherichia coli infection, Regulation of actin cytoskeleton

• Field of Research:

  Fc gamma R-mediated phagocytosis, Pathogenic Escherichia coli infection, Regulation of actin cytoskeleton

• Concentration:

  >50 ug/mL as determined by microplate BCA method

• Purity:

  > 80% as determined by SDS-PAGE and Coomassie blue staining

• Form:

  Liquid

• Buffer:

  25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol

• Molecular Weight:

  16.1 kDa

• Storage Conditions:

  Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.

• Symbol:

  ARPC5

• Species:

  Human

• Protein ID:

  NP_005708

• Overview:

  Recombinant protein of human actin related protein 2/3 complex, subunit 5, 16kDa (ARPC5)

• Gene ID URL:

  https://www.ncbi.nlm.nih.gov/gene/10092

• Uniprot URL:

  https://www.uniprot.org/uniprot/O15511

• Accession Number mRNA URL:

  https://www.ncbi.nlm.nih.gov/nuccore/NM_005717

• Protein ID Link:

  https://www.ncbi.nlm.nih.gov/nuccore/NP_005708