DEGS1 (NM_003676) Human Recombinant Protein

• Background:

  This gene encodes a member of the membrane fatty acid desaturase family which is responsible for inserting double bonds into specific positions in fatty acids. This protein contains three His-containing consensus motifs that are characteristic of a group of membrane fatty acid desaturases. It is predicted to be a multiple membrane-spanning protein localized to the endoplasmic reticulum. Overexpression of this gene inhibited biosynthesis of the EGF receptor, suggesting a possible role of a fatty acid desaturase in regulating biosynthetic processing of the EGF receptor. [provided by RefSeq, Mar 2010]

• Synonyms:

  DEGS; DEGS-1; Des-1; DES1; FADS7; HLD18; MIG15; MLD

• Gene ID:

  8560

• UniProt:

  O15121, A0A024R3P1

• Accession Number mRNA:

  NM_003676

• Chromosomal Location:

  1q42.11

• Expression System:

  HEK293T

• Tag:

  C-Myc/DDK

• Related Pathways:

  Metabolic pathways, Sphingolipid metabolism

• Field of Research:

  Metabolic pathways, Sphingolipid metabolism

• Concentration:

  >50 ug/mL as determined by microplate BCA method

• Purity:

  > 80% as determined by SDS-PAGE and Coomassie blue staining

• Form:

  Liquid

• Buffer:

  25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol

• Function:

  Druggable Genome, Transmembrane

• Molecular Weight:

  37.7 kDa

• Storage Conditions:

  Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.

• Symbol:

  DEGS1

• Species:

  Human

• Protein ID:

  NP_003667

• Overview:

  Recombinant protein of human degenerative spermatocyte homolog 1, lipid desaturase (Drosophila) (DEGS1), transcript variant 1

• Gene ID URL:

  https://www.ncbi.nlm.nih.gov/gene/8560

• Uniprot URL:

  https://www.uniprot.org/uniprot/O15121

• Accession Number mRNA URL:

  https://www.ncbi.nlm.nih.gov/nuccore/NM_003676

• Protein ID Link:

  https://www.ncbi.nlm.nih.gov/nuccore/NP_003667